Motesanib
Motesanib (AMG 706) is an orally administered small molecule inhibitor targeting VEGFR, PDGFR, Kit, and Ret receptor tyrosine kinases. It has been investigated in preclinical cancer research for its anti-angiogenic and anti-proliferative effects, with studies conducted in both in vitro and in vivo models.
Product Specifications
CAS Number
453562-69-1
Product Name Alternative
AMG 706, AMG-706, AMG706, CD117, cKit, c-Kit, inhibit, Motesanib, Inhibitor, SCFR, VEGFR3, VEGFR1, VEGFR2, VEGFR, Vascular endothelial growth factor receptor
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.36 mM) ; DMSO:50 mg/mL (133.89 mM)
Smiles
CC1 (C) CNc2cc (NC (=O) c3cccnc3NCc3ccncc3) ccc12
Molecular Formula
C22H23N5O
Molecular Weight
373.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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