KL-001
KL001 is a small molecule stabilizer of Cryptochrome (CRY) proteins that extends the circadian period by inhibiting CRY degradation. It suppresses glucagon-induced hepatic gluconeogenesis in vitro and serves as a key research tool for studying circadian biology and developing potential clock-modulating therapies for metabolic disorders like diabetes.
Product Specifications
CAS Number
309928-48-1
Product Name Alternative
CRY, cryptochrome, Cryptochrome protein (CRY), circadian, gluconeogenesis, inhibit, Inhibitor, KL001, KL-001, KL 001, period, stabilizer, ubiquitin
Field of Research
Cell Biology, Protein Biochemistry
Purity
>98%
Bioactivity
Cryptochrome (CRY) activator
Form
Powder
Solubility
Soluble in DMSO (up to 100 mg/ml) or in Ethanol (up to 20 mg/ml with warming) .
Smiles
CS (=O) (=O) N (CC (O) Cn1c2ccccc2c2ccccc12) Cc1ccco1
Molecular Formula
C21H22N2O4S
Molecular Weight
398.46
Storage Conditions
RT
Notes
For research use only.
Other Product Names
N-[3- (9H-Carbazol-9-yl) -2-hydroxypropyl]-N- (2-furanylmethyl) methanesulfonamide
Available Sizes
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