L-745870 trihydrochloride
L-745870 trihydrochloride is a potent and selective dopamine D4 receptor antagonist with moderate affinity for 5-HT2 receptors, sigma sites, and α-adrenoceptors. It is a valuable research tool for investigating D4 receptor function in neuropsychiatric disorders and has been utilized in both in vitro binding assays and in vivo behavioral studies.
Product Specifications
CAS Number
866021-03-6
Product Name Alternative
Brain-penetrant, Antipsychotic, 5HTReceptor, 5HT Receptor, 5-HT2, Adrenergic Receptor, AdrenergicReceptor, D4, D4-receptor, D3, D2, DopamineReceptor, Dopamine Receptor, orally, inhibit, L 745870, L 745870 trihydrochloride, L 745870 Trihydrochloride, Inhibitor, L-745,870, L-745,870 trihydrochloride, L-745,870 Trihydrochloride, L745870, L-745870, L745870 trihydrochloride, L745870 Trihydrochloride, L-745870 trihydrochloride, L-745870 Trihydrochloride, Sigmareceptor, Sigma receptor, α-adrenergic receptor, α-adrenoceptors
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
97.52% (May vary between batches)
Solubility
H2O:< 40 mg/mL; DMSO:50 mg/mL (114.62 mM)
Smiles
ClC1=CC=C (C=C1) N2CCN (CC2) CC3=CNC4=C3C=CC=N4.Cl.Cl.Cl
Molecular Formula
C18H22Cl4N4
Molecular Weight
436.21
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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