SB590885
SB590885 is a potent and selective B-Raf inhibitor with a Ki of 0.16 nM, demonstrating approximately 11-fold selectivity over c-Raf. This small molecule is a valuable research tool for investigating the RAF/MEK/ERK signaling pathway in both cellular and biochemical assays, supporting cancer research and targeted therapy development.
Product Specifications
CAS Number
405554-55-4
Product Name Alternative
B-Raf, inhibit, Inhibitor, SB590885, SB-590885, SB 590885, Raf kinases, Raf
Field of Research
Signal Transduction
Purity
95.42% (May vary between batches)
Form
Powder
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.41 mM) ; DMSO:12.5 mg/mL (27.56 mM)
Smiles
CN (C) CCOc1ccc (cc1) -c1nc (c ([nH]1) -c1ccncc1) -c1ccc2\C (CCc2c1) =N\O
Molecular Formula
C27H27N5O2
Molecular Weight
453.5
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
5-[2-[4-[2- (dimethylamino) ethoxy]phenyl]-5- (4-pyridinyl) -1H-imidazol-4-yl]-2,3-dihydro-1H-inden-1-one oxime
Available Sizes
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