ML-090
ML-090 is a potent and selective small molecule inhibitor of NADPH oxidase 1 (NOX1), exhibiting an IC50 of 90 nM. It demonstrates >100-fold selectivity over NOX2, NOX3, and NOX4 isoforms (IC50 >10 μM) . This inhibitor is a valuable research tool for studying NOX1's role in cellular redox signaling, inflammation, and cancer progression in both in vitro and in vivo models.
Product Specifications
CAS Number
531-46-4
Product Name Alternative
ML090, ML-090, ML 090, NADPHoxidase, NADPH Oxidase, NOX, NOX1, NOX2, NOX3, NOX4, inhibit, Inhibitor, Fluoflavine, HEK293 cell
Field of Research
Immunology & Inflammation, Metabolism Research
Purity
98.23% (May vary between batches)
Solubility
DMSO:< 1 mg/mL (insoluble or slightly soluble)
Smiles
N1c2ccccc2Nc2nc3ccccc3nc12
Molecular Formula
C14H10N4
Molecular Weight
234.26
Storage Conditions
-20°C
Notes
For research use only.
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