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Tenascin C (Stromal Marker For Epithelial Malignancy) Mouse Monoclonal Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

[TNC]

NCBI Gene ID

3371

Reactivity

Human.<br>Does not react with Rat

Storage Conditions

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

In Western blotting, it reacts with two bands of ~MW of 210kDa and 300kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linked hexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.

Other Gene Names

[TNC; TNC; GP; JI; TN; HXB; GMEM; TN-C; DFNA56; 150-225; HXB; TN; TN-C]

Short Name

[Tenascin C]

Other Product Names

[tenascin; Tenascin; tenascin; tenascin C; Cytotactin; GMEM; GP 150-225; Glioma-associated-extracellular matrix antigen; Hexabrachion; JI; Myotendinous antigen; Neuronectin; Tenascin-C; TN-C]

NCBI GI Number

153946395

NCBI Accession Number

NP_002151.2

NCBI GB Accession Number

NM_002160.3

Uniprot Accession Number

P24821

Available Sizes

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