Cytokeratin 8/18 Mouse Monoclonal Antibody
Product Specifications
Gene Name
[KRT8]
NCBI Gene ID
3856
Reactivity
Human
Storage Conditions
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This MAb cocktail recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained. Immuno-histochemical staining with this MAb is indistinguishable from that obtained with monoclonal antibody 5D3.
Other Gene Names
[KRT8; KRT8; K8; KO; CK8; CK-8; CYK8; K2C8; CARD2; CYK8; CK-8; K8]
Short Name
[Cytokeratin 8/18]
Other Product Names
[keratin, type II cytoskeletal 8 isoform 2; Keratin, type II cytoskeletal 8; keratin, type II cytoskeletal 8; keratin 8; Cytokeratin-8; CK-8; Keratin-8; K8; Type-II keratin Kb8]
NCBI GI Number
372466577
NCBI Accession Number
NP_001243222.1
NCBI GB Accession Number
NM_001256293.1
Uniprot Accession Number
P05787
CAS Number
9007-83-4
Available Sizes
Curated Selection
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