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N-tert-butyl-α-Phenylnitrone

N-tert-butyl-α-phenylnitrone (PBN) is a well-characterized spin trap and cyclooxygenase-2 (COX-2) inhibitor. Its ability to scavenge reactive oxygen species and cross the blood-brain barrier supports its use in neuroprotection, anti-inflammatory, and metabolic disease research in both cellular and animal models.

Product Specifications

CAS Number

3376-24-7

Product Name Alternative

Cyclooxygenase, COX-2, COX, (Z) -N-benzylidene-2-Methylpropan-2-aMine oxide, adducts, BBB, antioxidant, ERK, Inhibitor, iNOS, MAPK, inhibit, N tert butyl α Phenylnitrone, neuroprotective, N-benzylidene-2-Methylpropan-2-aMine Oxide, N-tert-butyl-alpha-Phenylnitrone, N-tert-butyl-a-Phenylnitrone, NtertbutylαPhenylnitrone, N-tert-butyl-α-Phenylnitrone, nitroxide, Reactive Oxygen Species, ROS, Scavenger, spin

Field of Research

Immunology & Inflammation, Metabolism Research, Neuroscience, Signal Transduction

Purity

99.46% (May vary between batches)

Solubility

DMSO:50 mg/mL (282.1 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (11.28 mM)

Smiles

CC (C) (C) [N+] ([O-]) =CC1=CC=CC=C1

Molecular Formula

C11H15NO

Molecular Weight

177.24

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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