N-tert-butyl-α-Phenylnitrone
N-tert-butyl-α-phenylnitrone (PBN) is a well-characterized spin trap and cyclooxygenase-2 (COX-2) inhibitor. Its ability to scavenge reactive oxygen species and cross the blood-brain barrier supports its use in neuroprotection, anti-inflammatory, and metabolic disease research in both cellular and animal models.
Product Specifications
CAS Number
3376-24-7
Product Name Alternative
Cyclooxygenase, COX-2, COX, (Z) -N-benzylidene-2-Methylpropan-2-aMine oxide, adducts, BBB, antioxidant, ERK, Inhibitor, iNOS, MAPK, inhibit, N tert butyl α Phenylnitrone, neuroprotective, N-benzylidene-2-Methylpropan-2-aMine Oxide, N-tert-butyl-alpha-Phenylnitrone, N-tert-butyl-a-Phenylnitrone, NtertbutylαPhenylnitrone, N-tert-butyl-α-Phenylnitrone, nitroxide, Reactive Oxygen Species, ROS, Scavenger, spin
Field of Research
Immunology & Inflammation, Metabolism Research, Neuroscience, Signal Transduction
Purity
99.46% (May vary between batches)
Solubility
DMSO:50 mg/mL (282.1 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (11.28 mM)
Smiles
CC (C) (C) [N+] ([O-]) =CC1=CC=CC=C1
Molecular Formula
C11H15NO
Molecular Weight
177.24
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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