Icotinib Hydrochloride
Icotinib Hydrochloride is an orally active quinazoline-derived EGFR tyrosine kinase inhibitor with antineoplastic potential. It effectively suppresses both wild-type and mutant EGFR activity, inhibiting downstream signaling and cancer cell proliferation, as demonstrated in various in vitro and in vivo oncology research models.
Product Specifications
CAS Number
1204313-51-8
Product Name Alternative
Inhibit, Inhibitor, Icotinib, Icotinib Hydrochloride, HER1, ErbB-1, Epidermal growth factor receptor, EGFR, EGFR mutants, BPI-2009H
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Purity
99.73% (May vary between batches)
Solubility
DMSO:12 mg/mL (28.05 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.67 mM)
Smiles
Cl.C#Cc1cccc (Nc2ncnc3cc4OCCOCCOCCOc4cc23) c1
Molecular Formula
C22H22ClN3O4
Molecular Weight
427.88
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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