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HS-173

HS-173 is a potent and selective small molecule inhibitor of PI3Kα, exhibiting an IC50 of 0.8 nM. It is a valuable research tool for studying the PI3K/AKT signaling pathway in cancer biology, applicable in both in vitro cellular assays and in vivo xenograft models for oncology research.

Product Specifications

CAS Number

1276110-06-5

Product Name Alternative

Apoptosis, Inhibitor, HS 173, HS173, HS-173, inhibit, PI3Kα, PI3K, Phosphoinositide 3-kinase

Field of Research

Cell Biology, Signal Transduction

Purity

99.33% (May vary between batches)

Solubility

Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:78 mg/mL (184.63 mM)

Smiles

CCOC (=O) c1cnc2ccc (cn12) -c1cncc (NS (=O) (=O) c2ccccc2) c1

Molecular Formula

C21H18N4O4S

Molecular Weight

422.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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