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Ornithine Decarboxylase-1 (ODC-1) Mouse Monoclonal Antibody

Product Specifications

Gene Name

[ODC1]

NCBI Gene ID

4953

Reactivity

Human, Rat

Storage Conditions

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

Recognizes a 53kDa protein, identified as the Ornithine Decarboxylase (ODC-1). ODC is the initial and rate-limiting enzyme in the biosynthetic pathway of polyamines and is involved in the conversion of ornithine to putrescine. The biological activity of ODC-1 is rapidly induced in response to virtually all agents known to promote cell proliferation including hormones, drugs, growth factors, mitogens, and tumor promoters. Reportedly, ODC mRNA levels are elevated in lung carcinomas as well as in colon adenomas and carcinomas. ODC activity in colorectal carcinomas is greater than those in adenomas and normal mucosa.

Other Gene Names

[ODC1; ODC1; ODC; ODC]

Short Name

[Ornithine Decarboxylase-1 (ODC-1)]

Other Product Names

[ornithine decarboxylase isoform 1; Ornithine decarboxylase; ornithine decarboxylase; ornithine decarboxylase 1]

NCBI GI Number

563580287

NCBI Accession Number

NP_001274118.1

NCBI GB Accession Number

NM_001287189.1

Uniprot Accession Number

P11926

CAS Number

9007-83-4

Available Sizes

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