CD18 / IntegrinBeta-2 (ITGB2) Mouse Monoclonal Antibody
Product Specifications
Gene Name
[ITGB2]
NCBI Gene ID
3689
Reactivity
Human.<br>Others not tested
Storage Conditions
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
It recognizes a transmembrane glycoprotein of 95kDa, identified as CD18 or integrin -2 (Workshop III). It complexes non-covalently with either L, M, or X integrin (CD11a, b, or c) to form the heterodimers, LFA-1, Mac-1, and p150,95, respectively. LFA-1 is the receptor for three members of the Ig supergene family of proteins, ICAM-1 (CD54), ICAM-2 (CD102), and Mac-1 and p150,95 bind to ICAM-1, fibrinogen, and iC3b. ICAM-3 (CD50). CD18/CD11 heterodimeric molecules are involved with cell/cell and cell/extracellular adhesion in immune and inflammatory responses. This MAb blocks these cellular interactions.
Other Gene Names
[ITGB2; ITGB2; LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1; CD18; MFI7]
Short Name
[CD18 / IntegrinBeta-2 (ITGB2)]
Other Product Names
[integrin beta-2 isoform 1; Integrin beta-2; integrin beta-2; integrin subunit beta 2; Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; Complement receptor C3 subunit beta; CD_antigen: CD18]
NCBI GI Number
735367775
NCBI Accession Number
NP_000202.3
NCBI GB Accession Number
NM_000211.4
Uniprot Accession Number
P05107
CAS Number
9007-83-4
Available Sizes
Curated Selection
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