PHA 568487 free base
PHA 568487 is a quinuclidine-based α7 nicotinic acetylcholine receptor agonist. Its design aimed to reduce metabolic bioactivation and improve in vivo tolerability of the core scaffold. This compound is used in neuroscience research to study α7 nAChR function in vitro and in vivo models.
Product Specifications
CAS Number
527680-56-4
Product Name Alternative
Ischemic, middle, macrophage, occlusion, nicotinic, memory, fracture, cerebral, artery, acetylcholine, α7 nAChR, polarization, Post-stroke, PHA568487, PHA-568487, PHA 568487 free base, PHA 568487
Field of Research
Metabolism Research, Neuroscience
Purity
99.00% (May vary between batches)
Solubility
H2O:< 40.44 mg/mL (100 mM) ; DMSO:30 mg/mL (104.04 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.94 mM)
Smiles
O=C (N[C@H]1CN2CCC1CC2) c1ccc2OCCOc2c1
Molecular Formula
C16H20N2O3
Molecular Weight
288.34
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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