CD106 / VCAM1 (Activated Endothelial Cell Marker) Mouse Monoclonal Antibody
Product Specifications
Gene Name
[VCAM1]
NCBI Gene ID
7412
Reactivity
Human
Storage Conditions
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Recognizes a protein of 110kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses. This MAb inhibits the binding of leukocytes to VCAM-1 on stimulated endothelial cells.
Other Gene Names
[VCAM1; VCAM1; CD106; INCAM-100; L1CAM; V-CAM 1; VCAM-1]
Short Name
[CD106 / VCAM1]
Other Product Names
[vascular cell adhesion protein 1 isoform a; Vascular cell adhesion protein 1; vascular cell adhesion protein 1; vascular cell adhesion molecule 1; INCAM-100; CD_antigen: CD106]
NCBI GI Number
4507875
NCBI Accession Number
NP_001069.1
NCBI GB Accession Number
NM_001078.3
Uniprot Accession Number
P19320
CAS Number
9007-83-4
Available Sizes
Curated Selection
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