Darunavir
Darunavir (TMC114) is a potent HIV-1 protease inhibitor used in antiretroviral therapy. To combat resistance, it is co-administered with other antiretroviral agents. It is widely used in research for studying viral replication, drug resistance mechanisms, and efficacy in both cellular and animal models of HIV infection.
Product Specifications
CAS Number
206361-99-1
Product Name Alternative
TMC114, TMC-114, TMC 114, UIC 94017, UIC94017, UIC-94017, Minimal, inhibit, Inhibitor, HIV Protease, HIVProtease, HIV, Human immunodeficiency virus, AID, cytotoxicity, Darunavir
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
98.00% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.65 mM) ; Ethanol:35 mg/mL (63.91 mM)
Smiles
O (C (N[C@H] ([C@@H] (CN (S (=O) (=O) C1=CC=C (N) C=C1) CC (C) C) O) CC2=CC=CC=C2) =O) [C@@H]3[C@]4 ([C@@] (OC3) (OCC4) [H]) [H]
Molecular Formula
C27H37N3O7S
Molecular Weight
547.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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