Dolutegravir sodium
Dolutegravir sodium (DTG) is a potent HIV integrase inhibitor (IC50: 2.7 nM) with activity against several raltegravir-resistant mutants. It is widely used in antiviral research for in vitro mechanistic studies and in vivo models of HIV infection, supporting the development of next-generation antiretroviral therapies.
Product Specifications
CAS Number
1051375-19-9
Product Name Alternative
GSK 1349572, GSK1349572, GSK-1349572, GSK-1349572A, HIV Integrase, HIV Protease, HIV, HIV integrase, HIVProtease, Inhibitor, Human immunodeficiency virus, inhibit, Dolutegravir, Dolutegravir sodium, S/GSK1349572
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
98.00% (May vary between batches)
Solubility
DMSO:4.42 mg/mL (10.01 mM)
Smiles
[Na+].C[C@@H]1CCO[C@H]2Cn3cc (C (=O) NCc4ccc (F) cc4F) c (=O) c ([O-]) c3C (=O) N12
Molecular Formula
C20H18F2N3NaO5
Molecular Weight
441.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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