Rilpivirine
Rilpivirine (R278474) is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor (NNRTI) active against HIV-1. It is utilized in antiretroviral therapy and is a key compound for in vitro virology research and in vivo studies investigating HIV treatment and drug resistance mechanisms.
Product Specifications
CAS Number
500287-72-9
Product Name Alternative
Transcriptase, Rilpivirine, ReverseTranscriptase, Reverse Transcriptase, reverse, resistance, R 278474, R278474, R-278474, TMC278, TMC-278, TMC 278, wild-type, HIV, HIV Protease, HIVProtease, Human immunodeficiency virus, Inhibitor, inhibit, non-nucleoside, mutant, NNRTI, DAPY, DB 08864, DB08864, DB-08864, diarylpyrimidine, antiviral
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
97.22% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (6.82 mM) ; DMSO:55 mg/mL (150.1 mM)
Smiles
N (C1=C (C) C=C (/C=C/C#N) C=C1C) C2=NC (NC3=CC=C (C#N) C=C3) =NC=C2
Molecular Formula
C22H18N6
Molecular Weight
366.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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