SB 204741
SB 204741 is a potent and selective 5-HT2B receptor antagonist, exhibiting a pKi of 7.1. This compound is a valuable research tool for investigating serotonin signaling in cardiovascular function, fibrosis, and neuropsychiatric disorders in both in vitro and in vivo models.
Product Specifications
CAS Number
152239-46-8
Product Name Alternative
5-hydroxytryptamine Receptor, 5HT Receptor, 5HTReceptor, affinity, 5-HT2B, 5-HT Receptor, human, Inhibitor, isoproterenol-induced, myocardial, inhibit, Serotonin Receptor, selective, SB 204741, SB204741, SB-204741, remodeling
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.83% (May vary between batches)
Solubility
Ethanol:< 5.73 mg/mL;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.98 mM) ; DMSO:50 mg/mL (174.61 mM)
Smiles
Cc1cc (NC (=O) Nc2ccc3n (C) ccc3c2) sn1
Molecular Formula
C14H14N4OS
Molecular Weight
286.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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