SB 452533
SB 452533 is a potent and selective vanilloid receptor 1 (TRPV1) antagonist with a pKb of 7.8. This compound is a valuable research tool for studying TRPV1-mediated pathways in pain, inflammation, and neurogenic disorders in both cellular and animal models.
Product Specifications
CAS Number
459429-39-1
Product Name Alternative
CAMKK2, capsaicin, ATP, inhibit, Inhibitor, ERK1/2, glucose oxidation, fibrosis, TRPVChannel, TRPV1, TRPV Channel, TRPChannel, TRP Channel, Transient receptor potential channels, skeletal muscle, pulmonary, SB 452533, SB452533, SB-452533
Field of Research
Pharmacology & Drug Discovery
Purity
98.52% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.32 mM) ; DMSO:60 mg/mL (159.45 mM)
Smiles
CCN (CCNC (=O) Nc1ccccc1Br) c1cccc (C) c1
Molecular Formula
C18H22BrN3O
Molecular Weight
376.29
Storage Conditions
-20°C
Notes
For research use only.
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