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SB 452533

SB 452533 is a potent and selective vanilloid receptor 1 (TRPV1) antagonist with a pKb of 7.8. This compound is a valuable research tool for studying TRPV1-mediated pathways in pain, inflammation, and neurogenic disorders in both cellular and animal models.

Product Specifications

CAS Number

459429-39-1

Product Name Alternative

CAMKK2, capsaicin, ATP, inhibit, Inhibitor, ERK1/2, glucose oxidation, fibrosis, TRPVChannel, TRPV1, TRPV Channel, TRPChannel, TRP Channel, Transient receptor potential channels, skeletal muscle, pulmonary, SB 452533, SB452533, SB-452533

Field of Research

Pharmacology & Drug Discovery

Purity

98.52% (May vary between batches)

Solubility

Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.32 mM) ; DMSO:60 mg/mL (159.45 mM)

Smiles

CCN (CCNC (=O) Nc1ccccc1Br) c1cccc (C) c1

Molecular Formula

C18H22BrN3O

Molecular Weight

376.29

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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