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SMANT hydrochloride

SMANT hydrochloride is a small molecule antagonist that inhibits Smoothened (Smo) accumulation. It is used in Hedgehog signaling pathway research for both in vitro and in vivo studies, including investigations into cancer and developmental biology.

Product Specifications

CAS Number

1177600-74-6

Product Name Alternative

N- (4-bromophenyl) -3- (3,5-dimethylpiperidin-1-yl) propanamide hydrochloride, N- (4-Bromophenyl) -3,5-dimethyl-1-piperidinepropanamide hydrochloride, hydrochloride, Hedgehog, Smoothened, SMANT HCl, SMANT Hydrochloride

Field of Research

Pharmacology & Drug Discovery, Stem Cell & Developmental Biology

Purity

99.81% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.32 mM) ; H2O:< 7.51 mg/mL; DMSO:35 mg/mL (93.15 mM)

Smiles

CN (C) CCN (Cc1ccccc1) C (=O) c1cc (-c2ccc (F) cc2) n2nc (cc2n1) C (C) (C) C

Molecular Formula

C16H24BrClN2O

Molecular Weight

375.73

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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PUS1 (Pseudouridylate Synthase 1, tRNA Pseudouridine Synthase A, Mitochondrial, tRNA Pseudouridine (38-40) Synthase, tRNA Pseudouridylate Synthase I, tRNA-uridine Isomerase I, MLASA1, PP8985) (APC)
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