SMER3
SMER3 is a cell-permeable small molecule inhibitor of the SCF (Met30) E3 ubiquitin ligase. It is a valuable research tool for studying ubiquitin-mediated proteolysis in processes such as cell cycle regulation, transcription, and immune signaling in both cellular and biochemical assays.
Product Specifications
CAS Number
67200-34-4
Product Name Alternative
Anticancer, E3 ligating enzyme, E2 conjugating enzyme, E1/E2/E3 Enzyme, E3 Ligase, E1 activating enzyme, Cullin, Inhibitor, inhibit, ligase, LigandforE3Ligase, Ligand for E3 Ligase, MET, SCF, Skp1, SMER 3, SMER3, SMER-3, Ubiquitin activating enzyme, ubiquitin, Ubiquitin conjugating enzyme, Ubiquitin ligase
Field of Research
Protein Biochemistry
Purity
>98%
Bioactivity
E3 Ubiquitin ligase inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 20 mg/ml) .
Smiles
O=C1c2ccccc2-c2nc3nonc3nc12
Molecular Formula
C11H4N4O2S
Molecular Weight
224.18
Storage Conditions
RT
Notes
For research use only.
Other Product Names
9H-Indeno[1,2-e][1,2,5]oxadiazolo[3,4-b]pyrazin-9-one
Available Sizes
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