Arginase 1 (Hepatocellular Carcinoma Marker) Mouse Monoclonal Antibody
Product Specifications
Gene Name
[ARG1]
NCBI Gene ID
383
Reactivity
Human; Others not known
Storage Conditions
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Non-hazardous. No MSDS required.
Specificity
Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes, which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.
Other Gene Names
[ARG1; ARG1]
Short Name
[Arginase 1]
Other Product Names
[arginase-1 isoform 2; Arginase-1; arginase-1; arginase 1; Liver-type arginase; Type I arginase]
NCBI GI Number
10947139
NCBI Accession Number
NP_000036.2
NCBI GB Accession Number
NM_000045.3
Uniprot Accession Number
P05089
CAS Number
9007-83-4
Available Sizes
Curated Selection
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