Sonepiprazole
Sonepiprazole (PNU-101387G) is a selective D4 dopamine receptor antagonist, with high affinity for rat (Ki=3.6 nM) and human D4.2 (Ki=10.1 nM) receptors and significantly lower affinity for D2 and H1 receptors. This selectivity makes it a valuable research tool for investigating D4 receptor function in neuropsychiatric disorders, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
170858-33-0
Product Name Alternative
Inhibit, Inhibitor, D4, DopamineReceptor, Dopamine Receptor, Sonepiprazole, PNU-101387G, U-101387G
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.31% (May vary between batches)
Solubility
DMSO:60 mg/mL (149.43 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.98 mM)
Smiles
C (CN1CCN (CC1) C2=CC=C (S (N) (=O) =O) C=C2) [C@H]3C=4C (CCO3) =CC=CC4
Molecular Formula
C21H27N3O3S
Molecular Weight
401.52
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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