Sulindac sulfone
Sulindac sulfone, a metabolite of the anti-inflammatory drug sulindac, acts as an aldose reductase inhibitor with an IC50 of 367 nM. This compound is utilized in research on diabetic complications, serving as a tool for in vitro enzymatic studies and in vivo metabolic investigations.
Product Specifications
CAS Number
59864-04-9
Product Name Alternative
Sulindac sulfone, Exisulind, Inhibitor, inhibit, Aldose Reductase, COX-2
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Modulates beta-catenin-mediated effects
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) .
Smiles
CC1=C (CC (O) =O) c2cc (F) ccc2\C1=C\c1ccc (cc1) S (C) (=O) =O
Molecular Formula
C20H17FO4S
Molecular Weight
372.41
Storage Conditions
RT
Notes
For research use only.
Other Product Names
(Z) -5-Fluoro-2-methyl-1-[p- (methylsulfonyl) benzylidene]indene-3-acetic acid
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