Enasidenib
Enasidenib (AG-221) is a small molecule inhibitor that selectively targets mutant IDH2 enzymes. It is used in research to study its effects in models of acute myeloid leukemia (AML), both in vitro and in vivo, for its potential to induce cellular differentiation.
Product Specifications
CAS Number
1446502-11-9
Product Name Alternative
AG-221
Field of Research
Metabolism Research, Pharmacology & Drug Discovery
Purity
>98%
Bioactivity
Mutant isocitrate dehydrogenase 2 (IDH2) inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml)
Smiles
CC (C) (O) CNc1nc (Nc2ccnc (c2) C (F) (F) F) nc (n1) -c1cccc (n1) C (F) (F) F
Molecular Formula
C19H17F6N7O
Molecular Weight
473.38
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
2-Methyl-1-[[4-[6 (trifluoromethyl) -2-pyridinyl]-6-[[2- (trifluoromethyl) -4-pyridinyl]amino]-1,3,5-triazin-2-yl]amino]-2-propanol
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