TASIN-1
TASIN-1 Hydrochloride is a selective small molecule that induces apoptosis in colorectal cancer cells expressing truncated APC. It acts by depleting cellular cholesterol, triggering ER stress and activating the ROS/JNK signaling pathway. This compound is a valuable research tool for studying APC-mutant cancer biology in both in vitro and in vivo models.
Product Specifications
CAS Number
1678515-13-3
Product Name Alternative
TASIN 1 HCl, TASIN 1 Hydrochloride, TASIN1 HCl, TASIN-1 HCl, TASIN1 Hydrochloride, TASIN-1 Hydrochloride, APC
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Induces apoptosis in cells with APC truncations
Form
Powder
Solubility
Soluble in DMSO (up to 20 mg/ml)
Smiles
CC1CCN (CC1) C2CCN (CC2) S (=O) (C3=CC=C (C=C3) OC) =O.[H]Cl
Molecular Formula
C18H28N2O3S·HCl
Molecular Weight
389.0
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
1-[1- (4-Methoxyphenyl) sulfonylpiperidin-4-yl]-4-methylpiperidine hydrochloride
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
