AZ-5104
AZ5104 is a selective and potent small molecule inhibitor of the epidermal growth factor receptor (EGFR) . It is widely used in biochemical and cellular assays to study EGFR-driven signaling pathways and has demonstrated research utility in both in vitro and in vivo models of oncology.
Product Specifications
CAS Number
1421373-98-9
Product Name Alternative
Inhibit, Inhibitor, HER1, HER2/ErbB2, EGFR, EGFR (L858R), EGFR (L861Q), EGFR (L858R/T790M), EGFR (wildtype), Epidermal growth factor receptor, ErbB-1, AZ5104, AZ-5104, AZ 5104
Field of Research
Cardiovascular Research, Signal Transduction
Purity
98.40% (May vary between batches)
Solubility
Ethanol:16 mg/mL (32.95 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.8 mM) ; DMSO:90 mg/mL (185.35 mM)
Smiles
COc1cc (N (C) CCN (C) C) c (NC (=O) C=C) cc1Nc1nccc (n1) -c1c[nH]c2ccccc12
Molecular Formula
C27H31N7O2
Molecular Weight
485.58
Storage Conditions
-20°C
Notes
For research use only.
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