Lomeguatrib
Lomeguatrib (PaTrin-2) is a small molecule inhibitor of the DNA repair protein MGMT (O6-methylguanine-DNA methyltransferase) . It is used in research to sensitize tumor cells to alkylating agents like temozolomide, both in vitro and in vivo, for studying chemotherapeutic resistance mechanisms.
Product Specifications
CAS Number
192441-08-0
Product Name Alternative
O6- (4-Bromothenyl) guanine
Field of Research
Epigenetics & Chromatin
Purity
>98%
Bioactivity
MGMT inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 10 mg/ml with warming)
Smiles
O (CC1=CC (Br) =CS1) C2=C3C (=NC (N) =N2) N=CN3
Molecular Formula
C10H8BrN5O3S
Molecular Weight
326.2
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
2-Amino-6-[ (4-bromo-2-thienyl) methoxy]-9H-purine
Available Sizes
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