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Torcetrapib

Torcetrapib (CP-529414) is a small molecule CETP inhibitor that blocks the transfer of cholesteryl esters from HDL to LDL/VLDL, thereby elevating HDL cholesterol levels. It has been widely used in cardiovascular research, including in vitro assays and animal studies, though its clinical development was halted due to adverse outcomes in Phase III trials.

Product Specifications

CAS Number

262352-17-0

Product Name Alternative

Cholesteryl ester transfer protein, cholesteryl, cholesterol, CETP, CP529414, CP-529414, CP 529414, ester, high-density, HDL, Inhibitor, inhibit, lipoprotein, lipoprotein LDL, low-density, triglycerides, transfer, Torcetrapib, protein, plasma, VLDL

Field of Research

Metabolism Research

Purity

98.00% (May vary between batches)

Solubility

DMSO:30 mg/mL (49.96 mM)

Smiles

CCOC (=O) N1[C@H] (CC) C[C@H] (N (Cc2cc (cc (c2) C (F) (F) F) C (F) (F) F) C (=O) OC) c2cc (ccc12) C (F) (F) F

Molecular Formula

C26H25F9N2O4

Molecular Weight

600.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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