Torcetrapib
Torcetrapib (CP-529414) is a small molecule CETP inhibitor that blocks the transfer of cholesteryl esters from HDL to LDL/VLDL, thereby elevating HDL cholesterol levels. It has been widely used in cardiovascular research, including in vitro assays and animal studies, though its clinical development was halted due to adverse outcomes in Phase III trials.
Product Specifications
CAS Number
262352-17-0
Product Name Alternative
Cholesteryl ester transfer protein, cholesteryl, cholesterol, CETP, CP529414, CP-529414, CP 529414, ester, high-density, HDL, Inhibitor, inhibit, lipoprotein, lipoprotein LDL, low-density, triglycerides, transfer, Torcetrapib, protein, plasma, VLDL
Field of Research
Metabolism Research
Purity
98.00% (May vary between batches)
Solubility
DMSO:30 mg/mL (49.96 mM)
Smiles
CCOC (=O) N1[C@H] (CC) C[C@H] (N (Cc2cc (cc (c2) C (F) (F) F) C (F) (F) F) C (=O) OC) c2cc (ccc12) C (F) (F) F
Molecular Formula
C26H25F9N2O4
Molecular Weight
600.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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