Canertinib dihydrochloride
Canertinib dihydrochloride (PD-183805 dihydrochloride) is an orally active quinazoline-based hydrochloride salt. It functions as a potent, irreversible pan-ErbB tyrosine kinase inhibitor, demonstrating antineoplastic and radiosensitizing properties in preclinical cancer research, including studies on breast and lung carcinoma models.
Product Specifications
CAS Number
289499-45-2
Product Name Alternative
PD183805, PD-183805, PD183805 Dihydrochloride, PD-183805 dihydrochloride, PD 183805, PD 183805 Dihydrochloride, HER2/ErbB2, EGFR, CI 1033, CI 1033 Dihydrochloride, CI1033, CI-1033, CI1033 Dihydrochloride, CI-1033 dihydrochloride
Field of Research
Cardiovascular Research, Infectious Disease & Virology, Signal Transduction
Purity
99.13% (May vary between batches)
Solubility
DMSO:59.38 mg/mL (106.25 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.58 mM)
Smiles
Cl.Cl.Fc1ccc (Nc2ncnc3cc (OCCCN4CCOCC4) c (NC (=O) C=C) cc23) cc1Cl
Molecular Formula
C24H27Cl3FN5O3
Molecular Weight
558.86
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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