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Plinabulin

Plinabulin is a potent vascular disrupting agent that binds tubulin at the colchicine site, depolymerizing microtubules and arresting the cell cycle. It demonstrates activity in both in vitro cytotoxicity assays and in vivo tumor models, making it a valuable research tool for studying angiogenesis and cancer therapeutics.

Product Specifications

CAS Number

714272-27-2

Product Name Alternative

Inhibitor, NPI2358, NPI-2358, NPI 2358, inhibit, MicrotubuleAssociated, Microtubule Associated, Microtubule/Tubulin, Plinabulin, Tubulin

Field of Research

Signal Transduction

Purity

91.68% (May vary between batches)

Solubility

DMSO:50 mg/mL (148.64 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.95 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

CC (C) (C) c1[nH]cnc1C=c1[nH]c (=O) c (=Cc2ccccc2) [nH]c1=O

Molecular Formula

C19H20N4O2

Molecular Weight

336.39

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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