Plinabulin
Plinabulin is a potent vascular disrupting agent that binds tubulin at the colchicine site, depolymerizing microtubules and arresting the cell cycle. It demonstrates activity in both in vitro cytotoxicity assays and in vivo tumor models, making it a valuable research tool for studying angiogenesis and cancer therapeutics.
Product Specifications
CAS Number
714272-27-2
Product Name Alternative
Inhibitor, NPI2358, NPI-2358, NPI 2358, inhibit, MicrotubuleAssociated, Microtubule Associated, Microtubule/Tubulin, Plinabulin, Tubulin
Field of Research
Signal Transduction
Purity
91.68% (May vary between batches)
Solubility
DMSO:50 mg/mL (148.64 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.95 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
CC (C) (C) c1[nH]cnc1C=c1[nH]c (=O) c (=Cc2ccccc2) [nH]c1=O
Molecular Formula
C19H20N4O2
Molecular Weight
336.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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