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VX-702

VX-702 is an investigational oral small molecule with high specificity for p38α MAPK, showing 14-fold selectivity over p38β. It has been studied in clinical trials for rheumatoid arthritis and is used in research to investigate p38α signaling in inflammatory disease models, both in vitro and in vivo.

Product Specifications

CAS Number

745833-23-2

Product Name Alternative

VX 702, VX702, VX-702, Inhibitor, inhibit, p38 MAPK, p38α, p38MAPK, Autophagy, 479543-46-9

Field of Research

Cell Biology, Signal Transduction

Purity

>98%

Bioactivity

P38a MAP kinase inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 2 mg/ml)

Smiles

NC (=O) N (c1ccc (C (N) =O) c (n1) -c1ccc (F) cc1F) c1c (F) cccc1F

Molecular Formula

C19H12F4N4O2

Molecular Weight

404.32

Storage Conditions

-20°C

Notes

For research use only.

Other Product Names

6-[ (Aminocarbonyl) (2,6-difluorophenyl) amino]-2- (2,4-difluorophenyl) -3-pyridinecarboxamide

Available Sizes

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