ABT-869
Linifanib (ABT-869) is a potent ATP-competitive inhibitor targeting VEGFR, PDGFR, and CSF-1R kinases. It demonstrates antiproliferative and pro-apoptotic activity in vitro, particularly against FLT3-dependent cancers, and has shown efficacy in reducing tumor growth in various in vivo xenograft models.
Product Specifications
CAS Number
796967-16-3
Product Name Alternative
Linifanib
Field of Research
Cardiovascular Research, Cell Biology
Purity
>98%
Form
Powder
Solubility
Soluble in DMSO (30 mg/ml)
Smiles
Cc1ccc (F) c (NC (=O) Nc2ccc (cc2) -c2cccc3[nH]nc (N) c23) c1
Molecular Formula
C21H18FN5O
Molecular Weight
375.4
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
1- (4- (3-Amino-1H-indazol-4-yl) phenyl) -3- (2-fluoro-5-methylphenyl) urea
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