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Amuvatinib

Amuvatinib (MP470) is an orally available small molecule investigational agent with potential antitumor properties. It has been studied in vitro and in vivo for its activity against various cancer cell lines, particularly in research focusing on receptor tyrosine kinase inhibition and DNA repair pathways.

Product Specifications

CAS Number

850879-09-3

Product Name Alternative

DNA Synthesis, DNASynthesis, cRET, CD117, Cluster of differentiation antigen 135, CD135, c-Kit, cKit, c-Kit (D816H), cMet, cMet/HGFR, c-Met, c-Met/HGFR, Apoptosis, Amuvatinib, inhibit, MP 470, MP470, MP-470, Platelet-derived growth factor receptor, PDGFR, Fms like tyrosine kinase 3, FLT3, FLT3 (D835Y), Inhibitor, HGFR, HPK56, HPK-56, HPK 56, RAD51, PDGFRα (V561D), RNA Synthesis, RNASynthesis, RET, SCFR

Field of Research

Cardiovascular Research, Cell Biology, Molecular Biology, Signal Transduction

Purity

98.48% (May vary between batches)

Solubility

DMSO:50 mg/mL (111.73 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.47 mM)

Smiles

C (NCC=1C=C2C (=CC1) OCO2) (=S) N3CCN (C4=C5C (C=6C (O5) =CC=CC6) =NC=N4) CC3

Molecular Formula

C23H21N5O3S

Molecular Weight

447.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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