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Butyrolactone I

Butyrolactone I (Olomoucin) is a potent, ATP-competitive inhibitor of CDK and cdc2 kinase families. It has demonstrated antitumor activity in vitro against various cancer cell lines, including non-small cell lung, small cell lung, and prostate cancers, making it a valuable tool for cell cycle and oncology research.

Product Specifications

CAS Number

87414-49-1

Product Name Alternative

CDK2, Cdc2/CyclinB, Butyrolactone I, Olomoucin

Field of Research

Cell Biology, Immunology & Inflammation, Signal Transduction

Purity

98.00% (May vary between batches)

Solubility

DMSO:80 mg/mL (188.48 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.77 mM)

Smiles

COC (=O) [C@]1 (Cc2ccc (O) c (CC=C (C) C) c2) OC (=O) C (O) =C1c1ccc (O) cc1

Molecular Formula

C24H24O7

Molecular Weight

424.44

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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