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p27Kip1 (Mitotic Inhibitor/Suppressor Protein) Mouse Monoclonal Antibody

Product Specifications

Gene Name

[CDKN1B]

NCBI Gene ID

1027

Reactivity

Human, Monkey, Mouse, Rat.<br>Others not known

Storage Conditions

Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

Recognizes a 27kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. Its epitope spans between aa 83-204 of p27. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This MAb co-precipitates cdk4 in complex p27Kip1 and is excellent for staining of formalin-fixed tissues.

Other Gene Names

[CDKN1B; CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1; KIP1]

Short Name

[p27Kip1]

Other Product Names

[cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor 1B; cyclin-dependent kinase inhibitor 1B; cyclin dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1]

NCBI GI Number

4757962

NCBI Accession Number

NP_004055.1

NCBI GB Accession Number

NM_004064.4

Uniprot Accession Number

P46527

CAS Number

9007-83-4

Available Sizes

Curated Selection

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