p27Kip1 (Mitotic Inhibitor/Suppressor Protein) Mouse Monoclonal Antibody
Product Specifications
Gene Name
[CDKN1B]
NCBI Gene ID
1027
Reactivity
Human, Monkey, Mouse, Rat.<br>Others not known
Storage Conditions
Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
Specificity
Recognizes a 27kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. Its epitope spans between aa 83-204 of p27. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. p27Kip1 functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. This MAb co-precipitates cdk4 in complex p27Kip1 and is excellent for staining of formalin-fixed tissues.
Other Gene Names
[CDKN1B; CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1; KIP1]
Short Name
[p27Kip1]
Other Product Names
[cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor 1B; cyclin-dependent kinase inhibitor 1B; cyclin dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27; p27Kip1]
NCBI GI Number
4757962
NCBI Accession Number
NP_004055.1
NCBI GB Accession Number
NM_004064.4
Uniprot Accession Number
P46527
CAS Number
9007-83-4
Available Sizes
Curated Selection
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