Ku (p70/p80) (Nuclear Marker) Mouse Monoclonal Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

[XRCC6]

NCBI Gene ID

2547

Reactivity

Human, Primates.<br>Does not react with Mouse, Rat and Chicken

Storage Conditions

Antibody with azide - store at 4 to 8 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

Recognizes a dimer of two proteins of 70kDa and ~80kDa, identified as two subunits of Ku. MAb KU729 recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Other Gene Names

[XRCC6; XRCC6; ML8; KU70; TLAA; CTC75; CTCBF; G22P1; G22P1; 5'-dRP lyase Ku70; CTC75; CTCBF; Ku70; TLAA]

Short Name

[Ku]

Other Product Names

[X-ray repair cross-complementing protein 6 isoform 1; X-ray repair cross-complementing protein 6; X-ray repair cross-complementing protein 6; X-ray repair cross complementing 6; 5'-deoxyribose-5-phosphate lyase Ku70; 5'-dRP lyase Ku70; 70 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 1; ATP-dependent DNA helicase II 70 kDa subunit; CTC box-binding factor 75 kDa subunit; CTC75; CTCBF; DNA repair protein XRCC6; Lupus Ku autoantigen protein p70; Ku70; Thyroid-lupus autoantigen; TLAA; X-ray repair complementing defective repair in Chinese hamster cells 6]