CD34 (Hematopoietic Stem Cell & Endothelial Marker) Mouse Monoclonal Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

[CD34]

NCBI Gene ID

947

Reactivity

Human

Storage Conditions

Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months.,Non-hazardous. No MSDS required.

Specificity

This MAb recognizes a single chain, transmembrane, heavily glycosylated protein of 90-120kDa, which is identified as CD34. Its expression is a hallmark for identifying pluripotent hematopoietic stem or progenitor cells. Its expression is gradually lost as lineage committed progenitors differentiate. CD34 is a marker of choice for staining blasts in acute myeloid leukemia. In addition, CD34 is expressed by soft tissue tumors, such as solitary fibrous tumor and gastrointestinal stromal tumor. Its expression is also found in vascular endothelium. Additionally, it appears that proliferating endothelial cells express this molecule more than the non-proliferating endothelial cells. Anti-CD34 labels > 85% of angiosarcoma and KAP'si s sarcoma, but with a lower specificity.

Other Gene Names

[CD34; CD34]

Short Name

[CD34]

Other Product Names

[hematopoietic progenitor cell antigen CD34 isoform a; Hematopoietic progenitor cell antigen CD34; hematopoietic progenitor cell antigen CD34; CD34 molecule; CD_antigen: CD34]