Levosimendan
Levosimendan (OR1259) is a calcium-sensitizing agent that enhances cardiac contractility by binding to cardiac troponin C, increasing myofilament calcium sensitivity without elevating intracellular calcium levels. It is widely used in cardiovascular research, particularly in studies of heart failure, employing both in vitro assays and in vivo animal models to investigate its inotropic and vasodilatory effects.
Product Specifications
CAS Number
141505-33-1
Product Name Alternative
OR1855, OR-1855, OR 1259, OR 1855, OR1259, OR-1259, KcsA, inhibit, Inhibitor, Levosimendan, Autophagy, Carbonic Anhydrase, CarbonicAnhydrase, Cardiac troponin C, Simsndan, phosphodiesterase, Phosphodiesterase (PDE), PotassiumChannel, Potassium Channel
Field of Research
Cell Biology, Metabolism Research, Pharmacology & Drug Discovery
Purity
99.32% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.14 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:45 mg/mL (160.55 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble)
Smiles
C[C@H]1C (C2=CC=C (NN=C (C#N) C#N) C=C2) =NNC (=O) C1
Molecular Formula
C14H12N6O
Molecular Weight
280.28
Storage Conditions
-20°C
Notes
For research use only.
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