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Ivabradine HCl

Ivabradine hydrochloride is a selective inhibitor of the hyperpolarization-activated cyclic nucleotide-gated (HCN) channel, blocking the If current in sinoatrial node cells to reduce heart rate. It is widely used in cardiovascular research, including in vitro electrophysiology studies and in vivo models of heart failure and angina, to investigate heart rate modulation.

Product Specifications

CAS Number

148849-67-6

Product Name Alternative

Hyperpolarization activated cyclic nucleotide gated channels, HCN Channel, HCNChannel, heart rate, Ivabradine, Ivabradine HCl, Ivabradine Hydrochloride, Ivabradine hydrochloride, inhibit, Inhibitor, anticonvulsant, anti-ischaemic, anti-anginal, Adrenergic Receptor, AdrenergicReceptor, orally active, S 16257-2

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

>98%

Bioactivity

Cardiac ion channel blocker

Form

Powder

Solubility

Soluble in DMSO (up to 20 mg/ml)

Smiles

N1 (C (=O) Cc2c (CC1) cc (c (c2) OC) OC) CCCN (C) C[C@@H]1c2c (cc (c (c2) OC) OC) C1.Cl

Molecular Formula

C27H36N2O5·HCl

Molecular Weight

505.05

Storage Conditions

RT

Notes

For research use only.

Other Product Names

3-[3-[[ (7S) -3,4-Dimethoxy-7-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-one hydrochloride

Available Sizes

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