CD56 / NCAM1 / NKH1 (Neuronal Cell Marker) Mouse Monoclonal Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

[NCAM1]

NCBI Gene ID

4684

Reactivity

Human, Rat

Storage Conditions

Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Specificity

This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the nodal and nasal NK/T-cell lymphomas.

Other Gene Names

[NCAM1; NCAM1; CD56; NCAM; MSK39; NCAM; N-CAM-1; NCAM-1]

Short Name

[CD56 / NCAM1 / NKH1]

Other Product Names

[neural cell adhesion molecule 1 isoform 1; Neural cell adhesion molecule 1; neural cell adhesion molecule 1; neural cell adhesion molecule 1; CD_antigen: CD56]