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Prucalopride

Prucalopride (R-93877) is a potent and selective agonist for the 5-HT4A and 5-HT4B receptors, exhibiting over 290-fold selectivity versus other 5-HT subtypes. It is widely used in gastrointestinal motility research, including in vitro receptor studies and in vivo models of colonic dysmotility and constipation.

Product Specifications

CAS Number

179474-81-8

Product Name Alternative

Pseudo-intestinal obstruction, Prucalopride, Serotonin Receptor, R 93877, R-93877, R93877, chronic constipation, A427, A549, 5-HT Receptor, 5-HT4A, 5-HT4B, 5HTReceptor, 5HT Receptor, 5-hydroxytryptamine Receptor, Inhibitor, Lung cancer, inhibit

Field of Research

Cell Biology, Neuroscience, Pharmacology & Drug Discovery

Purity

99.99% (May vary between batches)

Solubility

DMSO:56 mg/mL (152.23 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:36 mg/mL (97.86 mM)

Smiles

COCCCN1CCC (CC1) NC (=O) c1cc (Cl) c (N) c2CCOc12

Molecular Formula

C18H26ClN3O3

Molecular Weight

367.87

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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