Actin, Smooth Muscle (Leiomyosarcoma Marker) Mouse Monoclonal Antibody
Product Specifications
Gene Name
[ACTA2]
NCBI Gene ID
59
Reactivity
Human, Baboon, Monkey, Cow, Pig, Sheep, Goat, Cat, Dog, Rabbit, Mouse, Rat, Guinea Pig, Chicken
Storage Conditions
Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Non-hazardous. No MSDS required.
Specificity
Actin is a major component of the cytoskeleton and is present in most cell types. This MAb is highly specific to actin from smooth muscles. Its epitope lies in the first four N-terminal amino acids. This MAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.
Other Gene Names
[ACTA2; ACTA2; AAT6; ACTSA; MYMY5; ACTSA; ACTVS]
Short Name
[Actin]
Other Product Names
[actin, aortic smooth muscle; Actin, aortic smooth muscle; actin, aortic smooth muscle; actin, alpha 2, smooth muscle, aorta; Alpha-actin-2; Cell growth-inhibiting gene 46 protein]
NCBI GI Number
213688375
NCBI Accession Number
NP_001135417.1
NCBI GB Accession Number
NM_001141945.2
Uniprot Accession Number
P62736
CAS Number
9007-83-4
Available Sizes
Curated Selection
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