CD2
Product Specifications
Gene Name
[CD2]
NCBI Gene ID
914
Reactivity
Human.
Storage Conditions
Store at 2 to 8 °C. Antibody is stable for 24 months.
Specificity
CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.
Other Gene Names
[CD2; CD2; T11; SRBC; LFA-2; SRBC]
Short Name
[CD2]
Other Product Names
[T-cell surface antigen CD2; T-cell surface antigen CD2; T-cell surface antigen CD2; LFA-3 receptor; rosette receptor; erythrocyte receptor; lymphocyte-function antigen-2; T-cell surface antigen T11/Leu-5; CD2 antigen (p50), sheep red blood cell receptor; CD2 molecule; Erythrocyte receptor; LFA-2; LFA-3 receptor; Rosette receptor; T-cell surface antigen T11/Leu-5; CD_antigen: CD2]
NCBI GI Number
156071472
NCBI Accession Number
NP_001758.2
NCBI GB Accession Number
NM_001767.3
Uniprot Accession Number
P06729
Available Sizes
Curated Selection
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