Etravirine
Etravirine (R165335) is a second-generation diarylpyrimidine NNRTI effective against HIV strains resistant to first-generation NNRTIs. It inhibits reverse transcriptase by binding in multiple conformations. This compound is utilized in antiviral research for both in vitro enzymatic assays and in vivo studies of HIV infection and drug resistance.
Product Specifications
CAS Number
269055-15-4
Product Name Alternative
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry
Purity
>98%
Bioactivity
Anti-HIV agent
Form
Powder
Solubility
DMSO:250 mg/mL (574.34 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.59 mM)
Smiles
O (C1=NC (NC2=CC=C (C#N) C=C2) =NC (N) =C1Br) C3=C (C) C=C (C#N) C=C3C
Molecular Formula
C20H15BrN6O
Molecular Weight
435.28
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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