Cladribine

Cladribine (2CdA) is a purine nucleoside analog that acts as an adenosine deaminase inhibitor, used in research on lymphoproliferative disorders. It is applied in both in vitro and in vivo studies to investigate its cytotoxic mechanisms against malignant lymphocytes, such as in hairy cell leukemia.

Product Specifications

CAS Number

4291-63-8

Product Name Alternative

DLBCL, CLL, CldAdo, cell, Cladribine, chronic, Adenosinedeaminase, Adenosine Deaminase, Adenosine deaminase, Adenosine deaminase (MM1.S cells), Adenosine deaminase (RPMI8226 cells), Adenosine deaminase (U266 cells), 2-chlorodeoxyadenosine, 2CdA, 2-Chloro-2′-deoxyadenosine, Apoptosis, mucosa-associated, multiple, inhibit, lymphocytic, lymphoid, lymphoma, hairy, follicular, MCL, mantle, MALT, leukemia, HCL, Inhibitor, tissue, sclerosis

Field of Research

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery

Purity

99.00% (May vary between batches)

Solubility

Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:255 mg/mL (892.58 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (17.5 mM)